While penicillin was indeed originally developed ... The answer is explained by a phenomenon called cross-reactivity. Cross-reactivity means that there are similar proteins shared between certain ...

contain detectable amounts of penicillin. These amounts (1 to 200 units per milliliter) are sufficient to produce an allergic reaction in patients exquisitely sensitized. 1 In addition to this ...

2002; Scheman et al., 2008). Patients with a neomycin sensitivity may experience a cross-reaction with structurally related antibiotics such as gentamicin (Garamycin®), kanamycin, streptomycin ...

A systematic review and meta-analysis finds that the global prevalence of reported penicillin allergy is 9.4%, though most studies were from high-income countries.