NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

Human genetic diversity and evolution rely on new mutations and exchange of DNA between chromosomes during the generation of sex cells, in a process called recombination. Recombination manifests ...

A PCA is able to boil down a data set comprising hundreds or even thousands of dimensions (think the largest spreadsheet you’ve ever seen) into a 2D plot. (Or, depending on the type of analysis ...

This technological leap has resulted in a dazzling discovery: there was not one, but at least three separate waves of recent human–Neanderthal admixture in the last 250,000 years. The earliest ...

CRISPR gene cuts may offer new way to chart human genome Date: February 24, 2020 Source: Johns Hopkins Medicine Summary: In search of new ways to sequence human genomes and read critical ...

The output from a DNA sequencer. ... or “reference genome,” has serious limits because it doesn’t reflect the spectrum of human diversity.

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from ...

Ancient DNA Charts Native Americans’ Journeys to Asia Thousands of Years Ago Analysis of ten Eurasian individuals, up to 7,500 years old, gives a new picture of movement across continents ...

Every human's genome has millions of genetic variants, but most have little to no effect, ... Large-scale DNA sequence resource reveals new regions of the human genome under natural selection.

Known as the GRCh38 reference genome, it is periodically updated with DNA sequences from other individuals, but in a new analysis, Johns Hopkins scientists now say that the collective genomes of ...