Please note that the tovecimig/paclitaxel combo enjoys the FDA’s ... to treat patients with tumors expressing neural cell adhesion molecule (NCAM or CD56) in mid-2025. CMPX also reported that ...

Using high-resolution cryo-electron microscopy (cryo-EM) and single-molecule fluorescence microscopy ... inside the microtubules are inhibited by paclitaxel. Further investigation showed that ...

This groundbreaking finding suggests that Telomir-1 may selectively benefit healthy cells while suppressing malignant growth, challenging the assumption that telomere-elongating drugs inherently ...

Lapatinib is an oral, reversible, small-molecule dual inhibitor of EGFR and HER2 tyrosine kinases that has demonstrated clinical activity in treatment-naive patients with HER2-overexpressing ...

Under these conditions the paclitaxel-nocodazole differential manifests 12 —that is, in this case, small-molecule-mediated inhibition is phenocopied by mild overexpression of catalytic mutants ...

In the group treated with Paclitaxel alone ... Telomir is focused on the development of Telomir-1, a novel small molecule metal ion regulator designed to lengthen the DNA's protective telomere ...