Two patients experienced serious hypersensitivity reactions after the second paclitaxel infusion. Paclitaxel was therefore interrupted in these patients, while vinorelbine and 5-FU were maintained.

Briefly, dexamethasone (20 mg), oral diphenhydramine (50 mg), and intravenous ranitidine (50 mg) were administered 30 minutes before paclitaxel infusion.

Nab-paclitaxel does not require premedication for hypersensitivity reactions, has a shorter infusion time (30 min for nab-paclitaxel vs 3 h for CrEL-paclitaxel) and does not require special ...

Standard paclitaxel contains Cremophor EL as a solvent, thus requiring premedication with high doses of antihistamines and corticosteroids, as well as prolonged infusion times. Albumin-bound or ...

That delivery occurs through infusion sets, which comprise the medication cartridges and tubing necessary to connect the pump to the patient. The infusion pumps are portable and meant to be ...

The need for IV infusion also means patients have to go to a medical center to be treated, limiting global access to this medicine. An oral paclitaxel was the team's ultimate test of their sol ...

If your doctor stops nab-paclitaxel due to side effects you may still continue with atezolizumab on its own. You may have this once every 3 or 4 weeks. This depends on if you have it as an injection ...