The dose of paclitaxel used in the new approach was 16-fold lower than that typically used in free paclitaxel, but with similar efficacy.
Intravenous. 1 Paclitaxel 135 mg/m 2 by iv. infusion over 3 h Cisplatin 60 mg/m 2 iv. infusion over 3 h 15 Paclitaxel 135 mg/m 2 by iv. infusion over 3 h Etoposide 150 mg/m 2 iv. infusion over 1 h ...
The FDA granted an orphan drug designation to PEP-010 for the treatment of patients with metastatic pancreatic cancer.
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