New research indicates that a drug called Inavolisib is effective at treating a type of metastatic breast cancer with a ...

The PIK3CA gene, which encodes the p110α subunit of phosphoinositide 3-kinase (PI3K), is among the most frequently mutated oncogenes in cancer. These mutations drive tumor progression, metabolic ...

Scientists from UF’s College of Veterinary Medicine and the UF Health Cancer Center investigated how mutations in a gene called PIK3CA impact the development and progression of angiosarcoma.

PIK3CA mutations are frequently associated with breast cancer with a prevalence of around 40%. These are somatic mutations that code for PI3 kinases, and this, along with Akt and mTOR signaling ...

An expert explained a potential side effect associated with treatment consisting of Itovebi for breast cancer.

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The most common comorbidities using PIK3CA inhibitors, are hyperglycemia, diarrhea, and rash. In the SOLAR-1 Study that used Alpelisib, we found that 60% of patients experienced hyperglycemia ...

That may be because the non-biomarker group in the study included quite a high proportion of untested patients in whom PIK3CA/AKT1/PTEN status was unknown. Mutations in PIK3CA, AKT1, and ...

Researchers conduct a retrospective, population-based cohort study of adult patients with metastatic breast cancer who underwent genomic profiling at academic institutions.