Dopamine, a small molecule derived from the amino acid tyrosine, plays a significant role in regulating multiple essential ...

New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa ...

The compound provides non-opioid pain relief by targeting neurotensin receptor 1 (NTSR1) on sensory neurons and within the ...

The deal prepares for a pain treatment market rivalry with Vertex Pharmaceuticals as the industry starts to move away from ...

Researchers have taken a closer look at the molecular mechanisms of these active substances. Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the ...

differentiating this approach from traditional IBS treatments that primarily target peripheral mechanisms. These findings suggest that opioid delta-receptor activation modulates both peripheral ...

Use of the investigational non-opioid analgesic resiniferatoxin appeared to improve pain control in patients with advanced ...

Opioids alleviate pain by imitating a ... pharmacological experiments to comprehend the signaling mechanisms of these receptors. Speaking to Medical News Today, DiBerto explained the background ...

Duke University researchers have created SBI-810, an experimental compound that provides pain relief by selectively ...

“We’re also interested in understanding the causal mechanisms of these brain alterations,” said Mehta. “Future research could investigate whether the opioid receptors in these regions or their ...