Dopamine, a small molecule derived from the amino acid tyrosine, plays a significant role in regulating multiple essential ...

Duke scientists may have discovered a game-changing painkiller. SBI-810 is a new non-opioid drug that offers potent pain ...

New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa ...

Researchers have taken a closer look at the molecular mechanisms of these active substances. Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the ...

The deal prepares for a pain treatment market rivalry with Vertex Pharmaceuticals as the industry starts to move away from ...

differentiating this approach from traditional IBS treatments that primarily target peripheral mechanisms. These findings suggest that opioid delta-receptor activation modulates both peripheral ...

Opioids alleviate pain by imitating a ... pharmacological experiments to comprehend the signaling mechanisms of these receptors. Speaking to Medical News Today, DiBerto explained the background ...

We will test these same ligands for effects against opioid seeking (oxycodone),” he notes. The researchers will incorporate various protocols that allow rats to intravenously self-administer oxycodone ...

“We’re also interested in understanding the causal mechanisms of these brain alterations,” said Mehta. “Future research could investigate whether the opioid receptors in these regions or their ...