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They also identified biological mechanisms underlying these associations ... inflammation and membrane-weakening: the μ-opioid receptor, Toll-like Receptor 4 (TLR4), and the NLRP3 inflammasome.

This chemical bonded to opioid receptors in the mice's brains and triggered a feeling ... The researchers found the same neural mechanism in humans when studying donated brain tissue and scanning the ...

This newfound activation mechanism ... alternatives to opioids. The study is published in Proceedings of the National Academies of Sciences. Within cell membranes, ion channel receptors typically ...

In this systematic review, evidence for the efficacy of acute pain interventions on individuals with opioid use disorder was ...

The FDA approves a new non-opioid pain pill, Journavx, to treat acute pain in adults. It's a first-generation non-addictive ...

But he added that the back-to-back Phase 3 misses for Neumora and J&J against the kappa opioid receptor diminishes confidence in this target as a mechanism for treating major depressive disorder.

New research has identified cannabis-derived terpenes—compounds that give plants their distinctive aroma—as effective treatments for fibromyalgia and post-surgical pain ...