Three families of opioid peptides are well characterized; the endorphins, enkephalins and dynorphins. They bind to all three opioid receptors. Each family derives from a distinct gene; their ...

Nerve cells called pro-opiomelanocortin (POMC) neurons were found to be responsible for post-feeding sugar consumption.

For the first time in two decades, the Food and Drug Administration (FDA) has approved a new class of medication that provides an alternative to addictive opioids for patients looking to manage ...

The company tested cebranopadol, a dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist, in a late-stage trial on patients who have undergone cosmetic ...

Having shown last week that its opioid alternative can reduce post-surgery pain, Tris Pharma is back with another slice of clinical data to show that the drug is less likely to be abused.

Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

Cebranopadol is an investigational dual-nociceptin/orphanin FQ peptide receptor and µ-opioid peptide receptor (dual-NMR) agonist. The novel therapy is expected to provide pain relief while ...

creating a large and very urgent unmet medical need given the ongoing opioid crisis. Dr. Levitt will present Adolore's innovative CA8* chronic pain therapeutic (*carbonic anhydrase-like analgesic ...