Efavirenz increases CYP2C19- and CYP3A-mediated omeprazole metabolism. We hypothesized that CYP2C19 and CYP2B6 genetic polymorphisms influence the extent of induction of omeprazole metabolism by ...

The metabolism of esomeprazole and omeprazole is essentially similar, except that the rate of 5'-hydroxylation is slower in the case of esomeprazole than in the racemic mixture.

Brest, France -The proton pump inhibitor (PPI) omeprazole reduces the antiplatelet effect of clopidogrel, ... which are also involved in the metabolism of PPIs such as omeprazole.

However, the intestine has also been reported to be involved in first-pass extraction, and in some cases it is the major organ of drug metabolism 1, 2. Omeprazole is an atypical proton pump inhibitor.

Omeprazole comes in oral tablets, liquid suspension, and intravenous forms. Available in 10, 20, and 40-milligram […] The post 10 Things About Omeprazole That May Surprise You appeared first on ...