CYP2C19-mediated interactions Ticlopidine ↑ PPI effect Inhibition of omeprazole 5'-hydroxylation, decreased elimination Increased inhibition of gastric acid secretion Contraceptives ↑ PPI ...
The US FDA has also recently issued a warning stating, "new data show that when clopidogrel and omeprazole are taken together, the effectiveness of clopidogrel is reduced. Patients at risk for ...