This inhibition resulted in a significant reduction ... "With the potential to be used as a nucleic acid-based therapeutic, iSN40 could become an essential tool in addressing the growing ...

Nucleic acid therapeutics are based on nucleic acids ... and are typically considered in cases where specific inhibition of the function of a particular gene involved in disease is thought to ...

5) and to study its enzymatic properties, and soon thereafter, Miguel Ondetti and I began a fruitful collaborative effort to discover or design potent and specific inhibitors of ACE. The modern ...