Egyptian online auto parts marketplace Mtor has raised $2.8 million in pre-seed investment led by Egypt-focused venture capital firm Algebra Ventures. Other investors that participated in the ...

The strikes set off explosions in the capital of Tehran as Israel said it was targeting Iranian nuclear and military facilities. Among those killed were three of Iran’s top military leaders, one ...

mTOR stands for mammalian/mechanistic target of rapamycin. Rapamycin is an immunosuppressant drug that was first isolated from a bacterium found on Easter Island in the mid-20th Century.

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes awry. Scientists ...

Dr Marla Lipsyc-Sharf discusses how to best manage the challenging side effects associated with PIK3CA and mTOR Inhibitors to optimize patient care.

Sin1, a mTOR component, is crucial for T lymphocyte maturation, cytokine production, and immune niche regulation. Downregulation of mTORC1 and mTORC2 signaling facilitates antibacterial immunity ...

The PI3K/Akt/mTOR pathway is activated in the majority of pancreatic cancers, and inhibition of this pathway has antitumor effects in preclinical studies. We performed a multi-institutional, ...

The serine-threonine kinase mammalian target of rapamycin (mTOR) plays a major role in the regulation of protein translation, cell growth, and metabolism. Alterations of the mTOR signaling pathway are ...