Mitosis is a process of nuclear division in eukaryotic cells that occurs when a parent cell divides to produce two identical daughter cells. During cell division, mitosis refers specifically to ...

Importantly, nuclear envelope rupture was transient, as shown by the redistribution of the NLS–GFP signal, indicating that cells can restore nuclear membrane integrity during interphase.

Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA.

Lamin C facilitates repair of damaged nuclear envelope in human and mouse cells. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 10 / 221027132711.htm.

The nuclear envelope, for example, is a highly regulated membrane barrier that separates the nucleus from the cytoplasm; therefore, maintaining the integrity of the nuclear envelope is essential. In ...

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more ...

Study: LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion.Image Credit: Nemes Laszlo/Shutterstock Background. Metastasis, the migration of cancer cells from ...

Researchers have discovered that the proteins within this coating – known as the nuclear envelope – vary greatly between cells in different organs of the body.

Traditional genetic strategies of eliminating, altering, or increasing Ndc1 to test its function typically killed cells. "Having the exact right amount of Ndc1 is really critical," Jaspersen says.

Normal cells use the nuclear envelope tubules to repair DNA, but cancer cells appear to need them more. To explore the mechanism's potential impact, the team analyzed data representing over 8,500 ...

More information: Giel Korsten et al, Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair, Journal of Cell Biology (2024). DOI: 10.1083/jcb.202307142 Journal ...