Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into ...

In eukaryotic cells, the membrane that surrounds the nucleus — commonly called the nuclear envelope — partitions this DNA from the cell's protein synthesis machinery, which is located in the ...

A large structure called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. During prometaphase, the nuclear envelope that encloses the ...

"We think this research solves the mystery of how DNA double-strand breaks and the nuclear envelope connect for repair in ...

Cytoplasmic flows guide chromosome positioning during embryogenesis. During the first stages of animal embryo development, the egg cell undergoes multiple divisions without growin ...

The Maciejowski lab seeks to understand how the nuclear envelope safeguards the genome and prevents immune recognition of chromosomal DNA. We approach these problems using a combination of cell ...

Viral assembly involves a multi-step process, starting in the cell's nucleus with assembly ... and de-envelopment to travel across the nuclear envelope. This is followed by a secondary envelopment ...