NER operates somewhat differently on DNA that is transcriptionally active (transcription-coupled repair) and that which is transcriptionally silent (global genome repair). Defective NER in humans ...

Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions. The key steps in the NER ...

and then serves as a platform for the assembly of a DNA repair machine called nucleotide excision repair (NER) complex. NER then snips out faulty DNA found and replaces it with an accurate copy.

Nucleotide excision repair is a templated DNA-repair pathway that deals with bulky or helix-distorting lesions in DNA, such as ultraviolet (UV) light–induced pyrimidine dimers (interactive graphic).

What is the cellular DNA repair system (NER)? Nucleotide excision repair (NER) genes are responsible for the repair of DNA damage brought about by exogenous agents, such as UV light, chemicals ...

DNA damage repair is a critical process that all cells need to survive. NER is one of many DNA damage repair processes that attempts to remove UV or chemical-induced DNA damage so that replication ...

Like xeroderma pigmentosum (XP), Cockayne syndrome (CS) is a disease where elements of nucleotide excision repair (NER) do not work properly. The purpose of this repair mechanism is to remove DNA ...

Their work details how cells repair damaged DNA and preserve genes ... Sancar mapped out how cells use nucleotide excision repair to correct defects. Modrich solved the puzzle of how cells ...

A study has uncovered new findings about a DNA repair pathway called nucleotide excision repair and its role in the development of cancer. The paper also details how this defective pathway could be ...

A parallel process, global genome repair (GGR), was assumed to scan and fix most of DNA independent of transcription. Both processes were thought to set the stage for nucleotide excision repair ...