Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

Natural killer, or NK cells, are part of our innate immune system. A healthy body produces them to respond early during infection. They are activated and they kill cells infected with a given virus.

Michael Caligiuri, MD, discusses the modulation of natural killer cells to enhance their ability to detect and destroy tumor cells.

Experimental treatment could offer a safer, cheaper alternative to CAR-T-cell therapies for disorders such as lupus.

The six-year study focused on cyproheptadine, the active compound in the antihistamine Periactin. Periactin is commonly ...

Melbourne researchers have improved our understanding of how the immune system is regulated to prevent disease, identifying a previously unknown role of ‘natural killer’ (NK) immune cells.

Receptor engineering has significantly advanced NK cell-based cancer immunotherapies. As technical hurdles are overcome, ...

Natural killer (NK) cells are a type of lymphoid cell which function in the innate immune system to remove infected or cancerous self-cells. The innate immune system is the first line of defence ...

May 3, 2024 — Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body ...

And NK cells may be playing an unacknowledged role in other types of immunotherapy. Like T cells, NK cells have immune checkpoint molecules, such as CTLA-4 and PD-1. These molecules function like ...

Immune cells lose ‘killer instinct’ in cancerous tumors – but functionality can be re-awakened First study tracking how NK cells respond to the tumour microenvironment in real time ...