Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of ...

Diastolic heart failure is common in the elderly, particularly women. Previous studies on the value of brain natriuretic peptide in diastolic dysfunction have been largely limited to male subjects.

The chambers release peptide hormones, including ‘atrial natriuretic peptide’ and ‘brain natriuretic peptide’, which help regulate the balance of fluid in the body by affecting the kidneys.

Luís Beck-da-Silva, MD; Adolfo de Bold, PhD, FRSC; Ross A. Davies, MD, FRCPC; Benjamin J.W. Chow, MD, FRCPC; Terrence D. Ruddy, MD, FRCPC; Margaret Fraser, RN ...

Brain natriuretic peptide (BNP), first discovered in porcine brain, is principally produced by the heart. Unlike atrial natriuretic peptide (ANP), BNP is largely derived from the ventricles.