Histologically, KS is characterized by the presence of distinctive proliferating spindle-like cells, activated endothelial cells, fibroblast, smooth muscle ... of spindle cell morphology (Flore ...

The movement defects stem from abnormal morphology and low numbers of muscle spindles. Similar defects appeared in wild-type mice treated with the BACE1 inhibitor LY2811376, a Lilly compound that ...