This manuscript introduces a useful protein-stability-based fitness model for simulating protein evolution and unifying non-neutral models of molecular evolution with phylogenetic models. The model is ...

Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development ...

Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic ...

Blueprint Medicines is revising a pact with VantAI again, this time adding a focus for historically “undruggable” targets and ...

In a study published in Nature Communications, researchers at the University of Wisconsin–Madison introduced a deep learning ...

Proteins are among the most studied molecules in biology, yet new research shows they can still hold surprising secrets. Researchers have discovered previously undetected chemical bonds within ...

Researchers have identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the ...

Using brain mapping, genetic engineering and machine learning, scientists reveal how parasitic bacteria take over fruit fly ...

Australian researchers have discovered a molecule that may stop brain cell death linked to Alzheimer’s and Parkinson’s.