Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

With his team, he has now developed a theoretical model which explains the formation ... the interplay of filaments and motors is the mitotic spindle, which is responsible for correct cell division.

In an article published in the journal PloS Computational Biology, the scientists focused on the length of the mitotic spindle ... In this model, cell divisions are well characterized and ...

The molecular mechanisms that position the mitotic apparatus in stem cells are only starting to be unveiled and the available data are still scarce, but exciting. Figure 2: Spindle orientation and ...

At the other extreme, chromosomes with multiple centromeres are subject to fragmentation if the centromeres become attached to opposite spindle poles ... Figure 3 shows one model of how CENP ...