Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

More information: Cecilia Aquino-Perez et al, FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton, Proceedings of the National Academy of Sciences (2024).

In an article published in the journal PLoS Computational Biology, scientists used a data science approach to study the variations observed between different cells in spindle formation.

Figure 2: Mitotic centrosomes associated with ... First, because genetic deletions of Ncd suppress spindle collapse and the subsequent formation of microtubule mono-asters that otherwise occur ...