For initial treatment of symptomatic pulmonary sarcoidosis, methotrexate appeared to work as well as prednisone over 24 weeks, the randomized PREDMETH trial showed. Mean change from baseline in the ...

Doctors may prescribe either medication as an alternative to methotrexate. Taking DMARDs to treat PsA is also an off-label use. DMARDs can take several weeks or months to have a noticeable effect.

Methotrexate is a cheap ... Yet few are aware that it is used off-label to end ectopic pregnancies, or that it could be restricted by doctors or pharmacists even in states like Virginia that ...

For patients with pulmonary sarcoidosis, methotrexate is noninferior to prednisone with regard to the change from baseline to ...

The FDA and Health Canada "should also consider issuing warning labels to inform prescribers of the study's findings," the researchers wrote. Methotrexate is commonly prescribed for rheumatoid ...

Sometimes methotrexate is used off-label to end ectopic pregnancies, and use while pregnant can cause miscarriages or birth defects. Women with RA in states with restrictive abortion laws are now ...

Methotrexate has also been used off-label in the treatment of miscarriage and ectopic pregnancy, and it can be combined with misoprostol to induce abortion in early pregnancy. 4,6 Because ...

Patients who take methotrexate for a variety of immune-mediated ... they reported results from a randomized, open-label, superiority trial that suggested pausing the drug improved immunogenicity ...

The label expansion, announced Friday, combines Krystexxa with the chemotherapy and immunosuppressive drug methotrexate. In a randomized trial dubbed Mirror, Horizon demonstrated that patients on ...

Methotrexate is a strong drug that could help clear up your psoriasis. It’s part of a class of medications called antimetabolites that stop cells from dividing and slow their growth. In ...

A recent open-label, uncontrolled trial found that adding tacrolimus to the regimen of patients with a suboptimal response to methotrexate could be beneficial. After 6 months' treatment ...

Soon after she started taking the drug methotrexate in February, Jennifer Crow noticed a significant improvement in her inflammatory arthritis pain. Since then, she’s taken the drug weekly.