We examined the potential impact of these recommendations on metformin eligibility among U.S. adults. Conclusions The use of eGFR or CrCl to determine metformin eligibility instead of sCr can ...

Metformin, an oral medication used to treat type 2 diabetes, is often prescribed off-label for weight loss. It helps to control blood sugar by reducing both the amount of glucose produced by the ...

Renal insufficiency (CrCl 30–80mL/min ... May be antagonized by metformin.

Metformin, the first-line drug for diabetes, has low bioavailability and slow, incomplete gastrointestinal absorption. We hypothesized that gastric bypass would further reduce the absorption and ...