“This research significantly advances our understanding of metformin’s mechanism of action,” says corresponding author Navdeep Chandel from the Northwestern University Feinberg School of ...

“While millions of people take metformin, its mechanism of action has remained enigmatic,” said Navdeep Chandel, senior ...

However, people using metformin for its FDA-approved use may lose weight as a side effect. The exact mechanism of why weight loss may occur is unclear. Unlike other diabetes medications ...

This flux represents a novel target of metformin’s action in humans ... its underlying mechanisms remain not fully understood.” Gut microbes produce many substances that our body needs ...