Billions of years of evolution have made modern cells incredibly complex. Inside cells are small compartments called organelles that perform specific functions essential for the cell’s survival and ...

For this article, James Kling interviewed Thomas Weber, assistant professor in the department of gene therapy and molecular medicine at Mount Sinai School of Medicine. Data from the Web of Science ...

They identified two distinct modes of endosomal fusion: homotypic fusion, where two endosomes fuse rapidly to form a single vesicle, and heterotypic fusion, in which lysosomes slowly absorb endosomes.

Researchers who study membrane-driven processes such as synaptic communication, sperm-egg fusion, and viral infection have focused on the ways that proteins can regulate lipids to control membrane ...

When wild-type cells mate (top), mitochondria in the zygote show merged outer and inner membranes, as indicated by altered matrix color. ... Assay for inner mitochondrial membrane fusion.

Membrane fusion lies at the heart of many cell functions—from the secretion of antibodies to the release of neurotransmitters. For more than two decades, one view of the process by which ...

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological ...

Calcium/SNARE-dependent fusion machinery, cytoskeleton-dependent membrane tension, osmotic pressure, calcium/dynamin-dependent fission machinery, and actin/dynamin-dependent force machinery work ...

Study: The ACE-2 receptor accelerates but is not biochemically required for SARS-CoV-2 membrane fusion.Image Credit: Kateryna Kon/Shutterstock *Important notice: bioRxiv publishes preliminary ...

This type of simulation uses algorithms to predict how all the molecules of a specific system interact based on the ... Jaczynska K, Rosenmund C, Lin MM. Molecular mechanism underlying SNARE-mediated ...