OBJECTIVE: To examine and compare in vitro basal and insulin-stimulated glucose uptake in human omental and subcutaneous adipose tissue derived from lean, overweight or obese individuals, and in ...

The primary tissues involved in glucose utilization include the brain, muscle, fat, and the splanchnic area, with muscle tissue comprising the most important site of peripheral glucose uptake.

In affected people, insulin is unable to facilitate the uptake of glucose through tissues and organs, leading to an increase in blood glucose (chronic hyperglycaemia).

Some mammals are capable of hibernating during periods of low food availability in an effort to conserve energy and survive.

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2.

One way insulin does that is to accelerate the removal of glucose from blood and into muscle and fat cells. Key aspects of the mechanism for insulin to stimulate this glucose uptake remain to be ...

If you have diabetes, you may need to inject yourself with insulin. There are several different types of insulin and each one works a little differently.

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...

To better assess the effect of light on tissue sensitivity to insulin, researchers measured insulin-induced glucose absorption.

Insulin is a vital hormone that controls numerous processes in the body—from blood glucose (blood sugar) regulation to cell growth. Impaired insulin action is a major factor in the development ...

Since insulin is the hormone governing glucose uptake, insulin resistance often results in progressively increasing blood glucose levels, substantially increased prediabetes and type 2 diabetes ...