Enzyme mechanisms are the chemical transformations ... Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, however, the specific residues ...

A study reveals that the HDAC5 enzyme regulates the gene Scn4b, which affects neuronal activity in the brain's reward regions ...

Understanding the physical basis for this activity requires knowledge ... subject with the first and second editions of Enzyme structure and mechanism by Alan Fersht. The detailed introductory ...

The SCAN enzyme employs this mechanism, selectively nitrosylating target proteins such as the insulin receptor and its substrates. Interestingly, the researchers discovered elevated SCAN activity ...

Every year, thousands of tons of brown algae are extracted from the seabed to obtain compounds such as alginates, a polymer ...

"Our analyses now finally provide clarity about the mechanism and ... that of a specific enzyme, glycerol-3-phosphate ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

A study identifies senolytic compounds that can inhibit specific brain enzymes associated with Alzheimer’s disease (AD) while ...

Deviating from this range causes enzyme activity to slow down and eventually ... However, the precise molecular mechanisms behind this adaptation remain unclear. Understanding how enzymes from ...

However, the precise molecular mechanisms behind this adaptation ... "After that, we analyzed changes in enzyme activity at each evolutionary stage, especially improvements in catalytic activity ...

pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

After six years of warming, BG activity was ... and soil carbon-degrading enzyme activities to different warming magnitudes and durations and revealed the enzymatic mechanisms underlying SOC ...