Scientists identify mechanism for self-repair of thymus, a crucial component of the immune system
A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after ...
GEN4d
Mechanism for Self-Repair of the Thymus Identified
There is potential for Tregs and amphiregulin to be used in patients receiving cancer therapies to ameliorate immune function.
Nature3y
Revitope—third-generation T cell engager immunotherapies
Building on the lessons learned from the development of the first-and second-generation T cell engagers, Revitope used its deep knowledge of the mechanism of action of immune-based drugs as well ...
Medscape3d
Mechanisms of Disease: Pathogenesis of Crohn's Disease and Ulcerative Colitis
These studies indicate that Crohn's disease and ulcerative colitis are heterogeneous diseases characterized by various genetic abnormalities that lead to overly aggressive T-cell responses to a ...
HCW Biologics Granted FDA Clearance to Evaluate One of the Company’s Lead Product Candidates in a First-In-Human Phase 1 Clinical Trial
This study will evaluate HCW9302 in patients with moderate to severe alopecia areataMIRAMAR, Fla., Feb. 03, 2025 (GLOBE ...
HCW Biologics receives clearance of IND from FDA for HCW9302
HCW Biologics (HCWB) announced that it has received clearance of its Investigational New Drug Application, IND, from the U.S. Food and Drug ...
Phys.org1mon
Newly discovered mechanism triggers immune response in cells with damaged DNA
A research team from the University of California, Irvine has revealed a previously unknown mechanism that ... types of injury, cells release the IL-1α protein. It doesn't act on the cell itself ...