Ghrelin and leptin are two hormones which are of great interest in appetite regulation. Leptin is commonly considered to be anorexigenic (i.e. appetite suppressant) while ghrelin is orexigenic (i ...

Ever wondered why sometimes you feel like you could eat a horse or why those cravings just won't quit, even when you're ...

Leptin’s role is to send a message to stop eating when your body has had enough. When you’re sleep-deprived, your ghrelin level increases. At the same time leptin levels decrease.

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

New findings show that appetite-regulating peptides leptin and ghrelin influence alcohol craving. Leptin’s influence on craving is especially notable among patients of Lesch’s Type 1 and 2.

Here, we review the current understanding of the glucoregulatory functions of leptin, emphasizing its central mechanisms of action and lessons learned from clinical studies, and discuss possible ...

Ghrelin and leptin can promote and suppress osteoclastogenesis. These hormones interact to control bone metabolism and their relationship changes with age, according to a new study published in ...

To probe the mechanism of sleep in maintaining energy balance, the investigators measured the relationship of sleep, hunger, sympathovagal activity, and leptin in human volunteers in a sleep ...

A new study has confirmed that appetite-regulating peptides leptin and ghrelin do indeed influence alcohol craving, but especially among certain subtypes of alcoholics.

But now Bowen Tan, Kristina Hedbacker, and other researchers in Friedman's Laboratory of Molecular Genetics have discovered a neural mechanism involved in leptin resistance -- and, crucially, a ...