A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

The cancer-causing form of the gene Myc alters ... These three proteins represent a downstream target in the Myc pathway at which to aim drugs. Roughly 25 percent of all neuroblastoma cases ...

Cancer cells with elevated MYC expression often exhibit ... A current challenge is to identify additional synthetic lethal targets in these signaling pathways downstream of MYC. To date, both ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and ...

Their attention centered on the MYC pathway because of its known role in prostate cancer. They discovered that another protein and transcription factor, NME2, works closely with MYC in advanced ...

Medulloblastomas are one of the most common childhood brain cancers. University of Michigan researchers have now identified a ...

For decades scientists have known a specific gene, called MYC, plays a crucial role in the proliferation of cancer cells. The gene is often over expressed in a variety of different tumors ...

The protein produced by the MYC oncogene is a well-known foe in the oncology world. Its presence is associated with treatment-resistant cancer cells, which grow uncontrollably and evade the immune ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer ...