UC researchers have found how the MYC oncogene fuels lymphoma by altering cell metabolism, paving the way for targeted ...

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

a team of Moffitt Cancer Center researchers demonstrated a possible alternative approach. They showed that MYC activates a downstream pathway that chemically modifies a protein called eIF5A ...

Cancer cells with elevated MYC expression often exhibit ... A current challenge is to identify additional synthetic lethal targets in these signaling pathways downstream of MYC. To date, both ...

Their attention centered on the MYC pathway because of its known role in prostate cancer. They discovered that another protein and transcription factor, NME2, works closely with MYC in advanced ...

Preclinical data demonstrate preferential activity of MRT-2359, an orally bioavailable GSPT1-directed molecular glue degrader, in MYC-driven ... on the MYC pathway in cancer.

In healthy cells, the MYC protein is critical to the transcription process, where genetic information is converted from DNA to RNA and, eventually, into proteins. But, in cancer cells, MYC becomes ...

For decades scientists have known a specific gene, called MYC, plays a crucial role in the proliferation of cancer cells. The gene is often over expressed in a variety of different tumors ...

In a new study published in the journal Cell Reports Medicine, a team of scientists at Baylor College of Medicine took a closer look at the molecular pathways metastatic cancer cells use and ...