Similarly, do MYC-associated single nucleotide polymorphisms have a role in cancer development and ... is to functionally discriminate the genes, pathways and biological activities that MYC ...

Neuroblastomas are the most common cancer in infants, with about 700–800 diagnoses per year in the US, according to the American Cancer Society. Some of the most high-risk cases are driven by elevated ...

Scientists suggest understanding ecDNA’s role in pancreatic cancer could potentially guide future strategies for making ...

But eventually, the immune-attracting pathways are turned off ... some of the immune cells affected by excess MYC expression in prostate cancer -; are already in development and are potential ...

it is of utmost importance to conduct research on the molecular pathways underlying the ... in prostate cancer cell lines upon MYC suppression. Additionally, elevated levels of miR-377 in PCa ...

Monte Rosa Therapeutics’ plan to develop a molecular glue degrader in a wide range of cancers has come unstuck. | Monte Rosa ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...

which cause therapeutic vulnerabilities in breast cancer. Our current research specifically focuses on therapeutic strategies aiming to exploit MYC oncogene-induced vulnerabilities and therapeutically ...