Ascher JA; Cole JO; Colin JN; Feighner JP; Ferris RM; Fibiger HC; Golden RN; Martin P; Potter WZ; Richelson E BACKGROUND: The mechanism of action of the novel antidepressant bupropion remains ...
The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.
Bupropion HCl 150mg, 300mg; ext-rel tabs. Swallow whole. Avoid bedtime dosing. ≥18yrs: MDD: initially 150mg once daily in the AM for at least 4 days; if tolerated, increase to 300mg once daily ...