Materials marked for degradation are passed to late endosomes and eventually to lysosomes ... which plays a vital role in regulating endosome maturation. This gene encodes a deubiquitinating ...

Second, LPS-laden beads affect phagosome-lysosome fusion similarly in both ... particle does not affect the rate of phagosome maturation.

The maturation of early endosomes into lysosomes is marked by a progressive decrease in interior (luminal) pH, which is crucial for the activation of resident enzymes that degrade exogenous ...

This nanoplatform can actively target tumor regions and accumulate in the lysosomes of tumor cells ... of tumor-specific antigens and the maturation of dendritic cells, leading to the ...