A better understanding of lysosomal function may lead to new therapeutic strategies for these and other lysosome-related diseases. Now, in a new study published in the Journal of Cell Biology on ...

His review of the organelle's changing reputation was published in September's Journal of Cell Biology. As most high schoolers learn, the lysosome carries out waste disposal and recycling.

in Beijing who specializes in lysosomes and was one of the reviewers of the Nature Cell Biology article. Xiaochen Wang believes the work stands out because it was conducted in a living organism ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes ...

of Molecular Biology, and of Neurology, who is an expert on gene therapy for LSD patients. These results suggested STING drives neuroinflammation when lysosomes become damaged, a finding the ...

Details of this work appeared August 7 in the Journal of Cell Biology, in an article entitled “Impaired JIP3-Dependent Axonal Lysosome Transport Promotes Amyloid Plaque Pathology.” By ...

co-first-author of the study and MD-PhD candidate with the Integrated Biology and Medicine PhD track at Duke-NUS. "When lysosomes malfunction due to rare genetic disorders, this creates a build-up ...

cellular and developmental biology, discovered that if TMEM251 is defective, it fails to encode the pathway for the enzymes necessary for the correct function of lysosomes to travel inside the ...

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...