The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another. Therefore, the membrane lipids and proteins that are synthesized in ...

BORC-ARL8 is an essential regulatory factor in the fusion of lysosomes with autophagosomes ... presents significant challenges in structural biology. To overcome technical challenges such as ...

The autophagosome then fuses with another type of vesicle called a lysosome. The fused stage is called an autolysosome. The autolysosome ultimately matures into a lysosome, where the waste is ...

Lysosomes are organelles found within nearly ... proteins excreted through lysosomal exocytosis in cancer biology, particularly as to how cancerous cells might migrate through lysosomal activities.

Charlene earned her MSc and PhD in cell biology from the University of Toronto and currently ... the cell degrades them using lysosomes. We wanted to determine what happens to the cell when the ...

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say. Holly Barker is a freelance journalist ...

I am a cell physiologist and my research lab uses genetics, biochemistry, advanced microscopy and synthetic biology to study: (1) fundamental lysosome biology in health and disease, and (2) ...