Lubiprostone was significantly more effective in improving abdominal pain or bloating than placebo, according to results from a post-hoc analysis published in Alimentary Pharmacology and Therapeutics.

Amitiza (lubiprostone) is indicated for the treatment of CIC (24 mcg twice daily) in adults and for IBS-C (8 mcg twice daily) in women ≥18 years of age and older.

Washington, D.C. – May 21, 2007 -- A new study demonstrated that the active ingredient in AMITIZA® (lubiprostone), given 8 mcg twice a day, may improve symptom relief rates in adults with ...

Lubiprostone is a bicyclic, fatty-acid metabolite analog of prostaglandin E1. This compound acts locally to activate ClC-2 chloride channels, and has been shown to activate apical ClC-2, but not ...

September 26, 2012 (Phoenix, Arizona) — Constipation drug lubiprostone (Amitiza, Sucampo Pharmaceuticals, Takeda Pharmaceuticals) shows efficacy and tolerability in treating opioid-induced ...

Lubiprostone Significantly Improves Symptom Relief Rates in Adults with Irritable Bowel Syndrome and Constipation. Lubiprostone is a novel therapy indicated for treatment of chronic idiopathic ...

Study demonstrated AMITIZA (lubiprostone) showed efficacy Additional safety study finds AMITIZA also provided improvements in symptoms of chronic idiopathic constipation in long-term use ...

Lubiprostone increases fluid secretion into the intestinal tract. This increased fluid level softens the stool, facilitating intestinal motility and bowel movements.

Sucampo and Takeda Pharmaceuticals announced that lubiprostone met the primary endpoint in a Phase 3 clinical trial for the treatment of opioid-induced bowel dysfunction (OBD) in patients with ...

Sucampo Pharmaceuticals' (NASDAQ:SCMP) Lubiprostone treatment was effective and well tolerated in a trial of 127 of children and adolescents with functional constipation. "The results of this ...

Amitiza (lubiprostone) is indicated for the treatment of CIC (24 mcg twice daily) in adults and for IBS-C (8 mcg twice daily) in women ≥18 years of age and older.