Discover how sugar quietly damages your liver through dangerous mechanisms. Learn about fatty liver disease, inflammation, ...

Chronic liver diseases tied to metabolic dysfunction ... Notably, PTPRD deficiency also appeared to blunt insulin signaling. In primary human hepatocytes, silencing PTPRD reduced insulin-induced ...

"As a result, the pancreas produces more insulin to compensate ... may disrupt hunger and satiety signaling, leading to overeating and weight gain. The liver regulates fat metabolism.

Insulin orchestrates blood glucose levels by signaling fat and muscle cells to absorb the sugar and liver cells to stop pumping it out, so most research on insulin signaling focuses on these tissues.

A large new analysis found that soda and juice raise diabetes risk more than sweetened foods even when the sugar content is ...

1 “Defined PTPs act as endogenous inhibitors of insulin signaling by dephosphorylating ... insulin sensitivity and skeletal muscle and liver tissue, “leading to improved glucose tolerance ...

Adrenomedullin disrupts insulin signaling in blood vessels ... resistance is on the metabolic target organs of insulin such as liver, skeletal muscle, and adipose tissue,” the authors noted.

In healthy individuals, insulin signaling in the brain controls appetite ... Brain-specific effects of insulin action and fat content in the liver were assessed using MRI.