At the heart of a renaissance in lipid biochemistry, systems biology is being used to define ... of lipids was one of extreme diversity in structure, number and biochemical utility.

These START domain proteins differ markedly from SCP2, however, in that they are selective for one, but not both, lipids. The tunnel in the MLN64-START structure ... areas of biology where START ...

Interactions between proteins and lipids have diverse and complex roles in various biological processes, ranging from the structure, function, and dynamics of biological membranes to host-pathogen ...

Structural biology has made enormous contributions to a scientific understanding of protein structure and functions. In contrast, lipid molecules comprising biological membranes remains largely ...

Pharmaceutical scientists and biologists are teaming up to make the next generation of lipid nanoparticles (LNPs) for drug delivery. Combining structural biology with cutting edge pharmaceutical ...

The findings confirm longstanding suspicions that not only is this lipid a key player in cancer biology (and therefore ... lore because of their puzzling structure and function.

"The structure of the antibody itself holds an encoding principle to recognize lipids, which is something that was underappreciated before," Maillie says. Understanding these structural ...

In this month's issue of the Journal of Lipid Research, a group of Australian researchers report the structure of a key long-chain lipid ... by The American Society for Biochemistry and Molecular ...

With it, the Penn team achieved the stepwise optimization of ionizable lipid structure, a feat that hadn’t been achieved previously, despite the application of rational design and combinatorial ...