Their findings, published in npj Regenerative Medicine, reveal similarities and differences in metabolic signaling, lipid mobilization and storage between two regenerating species. In this project ...

Other important cellular functions involving phospholipids are: extracellular receptor signaling ... more sensitive methodologies will indicate lipids that modulate the targeting, trafficking ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

These structures revealed distinct binding modes and provided critical insights into the receptor's activation and signaling bias, highlighting the role of lipid interactions. Using advanced cryo ...

"We pinpointed a novel neurodegenerative microglia phenotype in Alzheimer's disease characterized by a stress-related signaling pathway ... and release toxic lipids. These lipids damage neurons ...