Explore a comprehensive guide to standardizing large scale production and clarification of lentiviral vectors.

Scientists have identified nanoparticles that latch onto and destroy virus membranes, opening new possibilities for antiviral ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Genetic medicines could treat certain diseases, however, the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For ...

Titania nanoparticles damage enveloped viruses by directly binding with membrane phospholipids – a previously unknown mode of antiviral action ...

SNALP is constructed by three basic lipids: an ionizable cationic lipid ... and lower toxicity in comparison with inorganic nanoparticles and viral vectors. Function-engineerable nanoparticles ...

Their distinctive properties such as innate stability, low immunogenicity, biocompatibility, and excellent tissue or cell penetration capabilities allow them to function as superior natural ...

Helper lipids contribute to the structural integrity and fusion with cell membranes. Cholesterol enhances the fluidity and stability of the nanoparticle, facilitating its fusion with cellular ...

A similar challenge arises at the microscopic level when lipid nanoparticles (LNPs) - the revolutionary drug delivery vehicles behind the COVID-19 vaccines - attempt to deliver mRNA to cells.

The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...

The 2nd Lipid Nanoparticle Development Europe Summit is returning this October with fresh, exclusive data to help you maximise this non-viral delivery system's potential. In collaboration with CPI ...

The viral vector analysis module in ASTRA software ... and quantify emerging bio-nanoparticles including viral vectors, lipid nanoparticles, and extracellular vesicles. Wyatt Technology, a ...