Charged nanoparticles can ... of liposomes — spherical lipid bilayer membranes that contain aqueous compartments — and measured the state of the membrane phases using fluorescence and calorimetry.

Cholesterol enhances the fluidity and stability of the nanoparticle, facilitating its fusion with cellular ... ionizable lipids respond to the acidic environment by altering their charge, which ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

Scientists have identified nanoparticles that latch onto and destroy virus membranes, opening new possibilities for antiviral ...

A new way to neutralize coronavirus and other membrane-surrounded viruses has been discovered by researchers from the Swedish ...

Genetic medicines could treat certain diseases, however, the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For ...

Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking ...

They are composed of a lipid core stabilized by surfactants or other agents ... and improving cellular uptake and membrane fusion. These advancements aim to provide safer and more effective non-viral ...

Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

Researchers at Tel Aviv University have achieved a major breakthrough in drug delivery: they have successfully transported lipid nanoparticles ... a natural biological membrane, which intestinal ...

The lipid nanoparticles that caused an immune response interacted with the cell membrane without disrupting its signaling ...