In further analyses, the researchers found that around 10% of these nerve cells have a receptor for the hormone leptin. Leptin is produced in adipose tissue and suppresses appetite in the brain.

In women, high leptin and obesity can boost the chances of breast cancer.Leptin-related inflammatory “cytokines” send signals that seem to impact how breast cancer cells grow and stay alive.

Leptin was only discovered in 1994, and scientists are still working to understand what leptin's role is. ... Leptin is a ...

Leptin is a hormone generated by fat cells. It signals your brain to tell your body when you’re full and should stop eating. Yet, people who are obese often develop leptin resistance.

Leptin gives a kind of green light signal to many other systems in the body. That includes your immune cells. A strong immune response is a good thing when you’re sick.

Leptin, produced primarily by fat cells, typically signals the brain when enough food has been consumed, helping to regulate ...

In lean individuals, fat cells produce the hormone leptin, which suppresses appetite. But in most individuals with obesity, this signal fails to register. Why this happens has been a mystery for more ...

Leptin is a cell-signalling hormone vital in the regulation of appetite, food intake and body weight. Studies have shown that an absence of leptin in the body or leptin resistance can lead to ...

Leptin plays an important role in regulating appetite and body weight. Leptin binds to a form of leptin receptor present in the cells of the hypothalamus. This stimulates an intracellular ...

They expected that keeping leptin out of circulation would damage their feeding behavior. Instead, they discovered surprising resilience. “The flies, when you starve them, have superpowers,” Rajan ...

Microenvironmental factors originating from RAS-mutated cancer stem cells stimulated an angiogenic feedback loop with the surrounding environment causing the expression of leptin and TGF-β receptors ...