Effector cells primarily undergo aerobic glycolysis, while memory cytotoxic T-cells exhibit enhance OXPHOS and fatty acid oxidation. Chronic infection or tumorigenesis impairs major metabolic ...

In this case, your body’s cells resort to breaking down carbohydrate stores for energy. Lactic acid – or, to use the physiologically accurate term, lactate – is produced as a result.

Prof. LIANG Xingjie's team from the National Center for Nanoscience and Technology, along with Prof. GONG Ningqiang from the University of Science and Technology of China, has developed a biomimetic ...

Exhausted T cells: Researchers map genome-wide changes that drive T cell maturation and exhaustion. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2016 / 12 ...

Minerva Biotechnologies - Overcoming the Solid Tumor Barrier: MUC1*-Targeted CAR T bearing 1XX mutations overcomes exhaustion and enables killing of low antigen expressing cancer cells ...

T cells that encounter too many tumor cell pieces can also become exhausted and lose their ability to kill cancerous cells. The researchers showed that removing Asxl1 prevented T-cell exhaustion ...