Young and his team first confirmed that the proteins play several key roles in ensuring that synaptic vesicles which contain ...

The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, ...

A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

Cellular communication between neurons within our brain is complex and busy, much like a USPS mailroom.To keep things running ...

All the data is publicly available online for use in scientific research. Approximately 75% of protein-coding genes in the human genome have been catalogued in corresponding knockout mouse models.

The knockout mice showed distinctly different characteristics in all of them. Related Stories Inhalable gene therapy tested for cystic fibrosis treatment in the UK and Europe ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...