Here we review hypotheses for the mechanism of action of ketamine as an antidepressant, including synaptic or GluN2B-selective extra-synaptic N-methyl-D-aspartate receptor (NMDAR) inhibition ...

Scientists from Sweden’s Karolinska Institutet have discovered a new mechanism to help illustrate the rapid antidepressant qualities of ketamine. The large study imaged patients with treatment ...

Looking closer, the researchers found a mechanism that could explain why ... ‘‘The consequence of this dual action of ketamine is that it does not induce the synaptic plasticity that addictive ...

Halloween party fights and the introduction of new 'swinger' Miranda, everyone's been left wondering - since when does ...

Psychedelics such as ketamine, psilocybin ... and Song et al presents the first comprehensive mechanism explaining how various psychedelics, each interacting with different combinations of ...

ketamine's "precise mechanisms" are unknown, but it's been found to be effective off-label in treating certain types of mental health struggles and past traumas. "Theories suggest it increases ...

This is possible only with an understanding, even an incomplete one, of ketamine’s mechanism of action, she says: “ ‘Why’ is not trivial.” John Krystal of Yale University, whose work ...

Researchers from Inserm, CNRS, Sorbonne University and clinicians from the AP-HP and at Paris Brain Institute identified one of the mechanisms explaining ketamine effect as an antidepressant.

recently received preclinical study data regarding the mechanism of action and toxicology data for its novel oral ketamine analog, Ketamir-2. Ketamir-2 is MIRA's drug candidate being investigated ...