The sound of the air conditioning and fans inside Norfolk Superior Court in Dedham have been an issue throughout both of Read's trials. Often during the first trial, when witnesses were testifying, their words could not be heard clearly in the courtroom because of the sound coming from the units, so Cannone ordered them to be turned off.

Judge Beverly Cannone dismissed a defense request for a mistrial after the prosecution questioned a witness about dog DNA in the Karen Read retrial.