However, the last thing Karev did before he left proves that what Jo Wilson (Camilla Luddington) worried about all along was true. Fans had no idea at the time, but Alex Karev’s last appearance ...

During Thursday’s Halloween episode of Grey’s Anatomy, Jo Wilson (Camilla Luddington) and Alex Karev (Justin Chambers) decided to tie the knot legally … in full Halloween costumes.

Grey’s Anatomy fans were heartbroken for Jo Wilson (Camilla Luddington) when Alex Karev (Justin Chambers) suddenly left her in season 16. Now, many viewers hope Jo will find happiness one day.

Time to say goodbye! Grey’s Anatomy finally gave some insight about Alex Karev’s (Justin Chambers) exit from the show during the Thursday, February 13, episode. Jo Wilson (Camilla Luddington ...

However, the one hurt the most by Karev’s choices was indubitably Jo Wilson. Ever since beginning their romantic relationship, Jo and Alex matched perfectly in their ability to take themselves ...

ABC promised us the March 5 episode would be Alex Karev's send ... featured Jo , best friend Meredith Grey (Ellen Pompeo) and former boss Miranda Bailey (Chandra Wilson) all reading letters ...

During Thursday’s season 16 midseason premiere of the ABC medical drama, Alex’s wife, Jo Wilson Karev (Camilla Luddington), addressed her husband’s absence. After Meredith Grey (Ellen Pompeo ...

After spending 15 years playing Alex Karev, Justin Chambers unexpectedly left the series without even a proper goodbye episode. Instead, Karev revealed in a breakup letter to his wife, Jo Wilson ...

"When I joined the show, very quickly Jo was with Alex, and so she sort of came as this package deal for many seasons,” Camilla Luddington tells PEOPLE Jo Wilson has come a long way on Grey's ...

Then going through a difficult time, Jo gave Alex “an out” as she signed herself into a psychiatric facility. But Alex wasn’t having it and proposed again after she finished her month-long ...

During Thursday’s Halloween episode of Grey’s Anatomy, Jo Wilson (Camilla Luddington) and Alex Karev (Justin Chambers) decided to tie the knot legally … in full Halloween costumes. Last season, the ...