PURPOSE OF REVIEW: T-cell interferon-gamma release assay (IGRA) use in tuberculosis (TB) contact screening and latent TB diagnosis is established and supported by American and European guidelines.

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

Figure 1: IFN-γ capture assay enriches tumor-reactive T cells from immunized mice. Figure 3: IFN-γ capture assay detects and enriches tumor-specific T cells from human RCC. In conclusion ...

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an assay that measured interferon gamma; and an assay that measured interleukin-17. Nearly three-quarters (73%) of participants achieved an immune response according to one of the three assays used.

They looked towards the interferon-gamma release assay (IGRA), a blood test initially developed to diagnose bTB in cattle. It works by measuring the levels of interferon-gamma (IFN-γ), a molecule ...

how HIF1α in T cells is key for induction of interferon gamma, or IFN-γ, in that hypoxic environment. The cytokine IFN-γ is known to be essential to induce the tumor-killing capacity of T cells.