Gene Therapy - Vector integration: Pest not guest. ... in the “pest” sequence category because targeting actively transcribed genes is likely to interfere with cellular function.

This function is considered by Zhou (1998) for the numerical integration of spiky functions. An & Owen (2001) approximate the function in d = 9 dimensions. ... In the equations above, ‖·‖ is the ...

A total of 2.9×10 4 unique integration sites representing 2.8×10 5 sequence reads were obtained from patients in the current trial and were compared with 1.3×10 4 unique integration sites ...