In the latest project, they focused on an insulin region, specifically a peptide, or a chain of amino acids—known as the B chain of insulin, or B:9-23—that is targeted by the immune cells in type 1 ...

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired ...

Hanson and Stevens 1 recently reported the cocrystal structure of the botulinum neurotoxin B light chain in complex with a 38-residue target peptide of synaptobrevin II. Based on a careful ...